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From historical cases suggestive of multiple sclerosis and the 1838 clinical description of MS to the latest research, Dr. Herndon (neurology, U. of Mississippi Medical Center, Jackson) provides an overview of developments relating to this central nervous system autoimmune disease. In this companion volume to Multiple sclerosis: diagnosis, medical management, and rehabilitation (Demos, 2000), US contributors to 16 chapters offer an overview of advances in the basic sciences and technologies as they pertain to understanding immune responses in MS (e.g., an animal model of demyelinating disease, identification of contributory infectious agents). The final chapter offers hope for remyelination of nerve fibers and recovery of function. Coverage of epidemiology and genetics is acknowledged as minimal.
Posted October 8, 2004
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