decades of molecular research, a cancer drug leaves the lab
Rowley's 1972 discovery paved the way for a leukemia-targeting
interferon chemotherapy failed to curb John Loecke's chronic myeloid
leukemia, University of Chicago oncologist Richard A. Larson recommended
a bone-marrow transplant, a risky but sometimes curative treatment
for Loecke's form of blood cancer. With seven brothers and sisters,
the 58-year-old retired middle-school principal had a good shot
at finding a compatible donor. But no sibling matched, and Loecke's
white blood-cell count rose dangerously high. He had already survived
for three years since learning he had this leukemia; the average
life span after diagnosis is four years.
Jeffersonian law of the land
was legislators, Currie argues in The Constitution in Congress:
The Jeffersonians, 1801-1829 (Chicago, 2001), who took the
lead in elucidating those intentions in the era from Thomas Jefferson's
inauguration in 1801 to Andrew Jackson's election in 1829. "The
Constitution was interpreted by members of Congress and by numerous
executive officers, up to and including the president," Currie
says. "Whenever a federal official proposed to take a particular
action, he always had to ask himself, 'Is it Constitutional?'"
Oysters to go?
all the factors contributing to the collapse of coastal ecosystems,
overfishing appears to be the worst-and not only the industrial
fishing of the 20th century. Humans have been overfishing for
centuries, says professor of geophysical sciences Susan Kidwell.
The problem is, we have a taste for the sea's most important creatures:
top predators like cod and water-filterers like oysters.
94, Number 1
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